Fluorescent liposomes are a type of liposome that is labeled with a fluorescent dye（DiI, DiO, DiD, DiR and DiA）, allowing for easy visualization and trace. Their fluorescent labeling allows for real-time tracking of their movement and accumulation, making them useful for studying drug delivery and biodistribution( specific cells or tissues). Additionally, they can be used in imaging applications such as FACS, fluorescent microscopy and bioimaging.

Mission: Target Technology  is committed to providing all individuals with the opportunity to get macrophages research experience. We offer technical expertise to advance comprehensive solutions to a broad range of macrophage research, with a particular focus on addressing the needs of macrophages isolation, enrichment, identification, depletion and trace.

Overview: Macrophages play an important role in immune and non-immune defence mechanisms. They form a first line of defence against bacterial, viral and other forms of microbiological contamination penetrating into the bodies of vertebrates. Macrophages are large cells, found in almost all bodily tissues where they can have varying forms and names (e.g. Kupffer cells, alveolar macrophages, microglia, osteoclasts, red pulp macrophages). Macrophages “scavenge”, they ingest and digest all foreign substances, microbes, cancer cells and cellular debris that might be potential pathogens. This process is called phagocytosis. Macrophages further regulate functions of many non-phagocytic cells, mainly through mediation of soluble molecules such as cytokines and chemokines. They are involved in innate immunity, adaptive immunity and can have (anti-) inflammatory effects.

Liposomes are artificially prepared spheres and consist of concentric phospholipid bilayers. When phospholipids are dispersed in water, the hydrophilic heads will make up both outer parts of the liposome, whereas the hydrophobic fatty acid groups will make up the inner part . Aqueous compartments separate the bilayers, and hydrophilic molecules can be dissolved in it, resulting in liposome-encapsulated molecules.

Fluorescent liposomes are a type of liposome that is labeled with a fluorescent dye, allowing for easy visualization and tracking. These artificial lipid vesicles are commonly used as delivery vehicles for drugs and other molecules in biological and medical research. We offer a range of sizes and dye options for fluorescent liposomes, which are composed of high-quality phospholipids and cholesterol to ensure stability and reproducibility in experiments.

Fluorescent liposomes have many potential applications in drug delivery, imaging, and diagnostics. They can be loaded with various drugs or other molecules and modified with targeting ligands to selectively deliver cargo to specific cells or tissues. Their fluorescent labeling allows for real-time tracking of their movement and accumulation, making them useful for studying drug delivery and biodistribution. Additionally, they can be used in imaging applications such as fluorescent microscopy and bioimaging. Fluorescent liposomes also have potential in diagnostic assays to detect disease markers or to monitor treatment response.