Committed to rapidly developing the liposomal drug, Target Technology provides customized conventional liposome formulation services, including formulation design, drug packaging services, and product characterization. Based on advanced technology platforms and strong expertise, we can customize the production of liposome with various types of drug loading for you.

Introduction to Conventional Liposomes

Conventional liposomes, the first generation of liposomes, are a family of vesicular structures based on lipid bilayers surrounding aqueous compartments (figure ). These particles are typically composed of only phospholipids (neutral and/or negatively charged) and/or cholesterol without modification. With its hydrophobic lipid bilayer and the hydrophilic aqueous space, various types of drug compounds could be incorporated accordingly. Off-the-shelf particles are normally supplied as lyophilized or pre-liposome powder form. Custom made liposomal formulation can be rationally designed with high versatility to increase drug delivery efficiency, by being very flexible systems through changing their physicochemical properties such as size, lipid composition, surface charge and number and fluidity of the phospholipid bilayer. Compared to free drugs, conventional liposomal formulations enhance drug delivery by reducing the toxicity of compounds, improving drug biodistribution, modifying pharmacokinetics. 

Our Featured Services

● Liposome formulation design: we customize liposomes design based on our clients’demand by varying lipid compositions, vesicle sizes, surface charges, etc.

● Liposome encapsulation: we employ customized protocols to encapsulate drug molecules into liposome with high encapsulation efficiency.

● Liposome-drug complex analysis and characterization: we can offer comprehensive analysis assays for liposomes before and after encapsulation, which includes visual appearance, size distribution, stability, Zeta potential, lamellarity, entrapment efficiency, and release rate.

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